The Great Work of Alchemy is the spiritual nature of personal transformation. It can be painful and costly, but in the end, the reward is your true self. The Great Work in Alchemy is fire and pain, but the reward, is You.
Alchemy is alive today.
In centuries past, Alchemists concerned themselves with the transmutation of base metals into gold and the perfection of body and soul was believed to arise from the alchemical magnum opus, or "Great Work."
In alchemy, the crucible is a melting-pot for metals involved in that transmutation or purification process.
I know of no alchemist who has succeeded in transmuting iron or lead into gold, but Alchemy as a metaphor for individual transformation, thrives today.
It thrives because the message and the imagery are so relevant to anybody who wishes to transform themselves.